Associated Genetic Biomarkers
ARID1A Frameshift is present in 2.88% of AACR GENIE cases, with endometrial endometrioid adenocarcinoma, colon adenocarcinoma, bladder urothelial carcinoma, breast invasive ductal carcinoma, and lung adenocarcinoma having the greatest prevalence .
ARID1A Frameshift serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ARID1A Frameshift as an inclusion criterion, 1 is phase 1 (1 open).
Trials with ARID1A Frameshift in the inclusion eligibility criteria most commonly target malignant solid tumor and ovarian serous tumor .
Vx-803 is the most frequent therapy in trials with ARID1A Frameshift as an inclusion criteria .
Significance of ARID1A Frameshift in Diseases
Malignant Solid Tumor +
ARID1A is mutated in 7.62% of malignant solid tumor patients with ARID1A Frameshift present in 2.97% of all malignant solid tumor patients .
ARID1A Frameshift is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains ARID1A Frameshift and malignant solid tumor as inclusion criteria, 1 is phase 1 (1 open) .
Ovarian Serous Tumor +
ARID1A is mutated in 4.21% of ovarian serous tumor patients with ARID1A Frameshift present in 0.75% of all ovarian serous tumor patients .
ARID1A Frameshift is an inclusion criterion in 1 clinical trial for ovarian serous tumor, of which 1 is open and 0 are closed. Of the trial that contains ARID1A Frameshift and ovarian serous tumor as inclusion criteria, 1 is phase 1 (1 open) .
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