Associated Genetic Biomarkers
ATM G2765S is present in 0.01% of AACR GENIE cases, with diffuse large B-cell lymphoma, not otherwise specified having the greatest prevalence .
ATM G2765S serves as an inclusion eligibility criterion in 2 clinical trials, of which 1 is open and 1 is closed. Of the trials that contain ATM G2765S as an inclusion criterion, 1 is phase 1 (1 open) and 1 is phase 2 (0 open).
Trials with ATM G2765S in the inclusion eligibility criteria most commonly target malignant solid tumor and small cell lung carcinoma .
Vx-803 and olaparib are the most frequent therapies in trials with ATM G2765S as an inclusion criteria .
Significance of ATM G2765S in Diseases
Malignant Solid Tumor +
Small Cell Lung Carcinoma +
ATM is altered in 3.75% of small cell lung carcinoma patients .
ATM G2765S is an inclusion criterion in 1 clinical trial for small cell lung carcinoma, of which 0 are open and 1 is closed. Of the trial that contains ATM G2765S and small cell lung carcinoma as inclusion criteria, 1 is phase 2 (0 open) .
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