Associated Genetic Biomarkers
ATR Deletion serves as an inclusion eligibility criterion in 2 clinical trials, of which 2 are open and 0 are closed. Of the trials that contain ATR Deletion as an inclusion criterion, 2 are phase 2 (2 open).
Trials with ATR Deletion in the inclusion eligibility criteria most commonly target breast carcinoma and pancreatic adenocarcinoma .
Olaparib is the most frequent therapy in trials with ATR Deletion as an inclusion criteria .
Significance of ATR Deletion in Diseases
Breast Carcinoma +
ATR is mutated in 2.9% of breast carcinoma patients with ATR Deletion present in 0.1% of all breast carcinoma patients .
ATR Deletion is an inclusion criterion in 1 clinical trial for breast carcinoma, of which 1 is open and 0 are closed. Of the trial that contains ATR Deletion and breast carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
Pancreatic Adenocarcinoma +
ATR is mutated in 0.9% of pancreatic adenocarcinoma patients .
ATR Deletion is an inclusion criterion in 1 clinical trial for pancreatic adenocarcinoma, of which 1 is open and 0 are closed. Of the trial that contains ATR Deletion and pancreatic adenocarcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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