BRAF Codon 596 Missense
Associated Genetic Biomarkers
BRAF Codon 596 Missense serves as an inclusion eligibility criterion in 3 clinical trials, of which 3 are open and 0 are closed. Of the trials that contain BRAF Codon 596 Missense as an inclusion criterion, 1 is phase 1 (1 open), 1 is phase 1/phase 2 (1 open), and 1 is phase 2 (1 open).
Trials with BRAF Codon 596 Missense in the inclusion eligibility criteria most commonly target malignant solid tumor and melanoma .
Rmc-4630, sar442720, binimetinib, cobimetinib, and encorafenib are the most frequent therapies in trials with BRAF Codon 596 Missense as an inclusion criteria .
Significance of BRAF Codon 596 Missense in Diseases
Malignant Solid Tumor +
BRAF is altered in 5.41% of malignant solid tumor patients with BRAF Codon 596 Missense present in 0.04% of all malignant solid tumor patients .
BRAF Codon 596 Missense is an inclusion criterion in 3 clinical trials for malignant solid tumor, of which 3 are open and 0 are closed. Of the trials that contain BRAF Codon 596 Missense and malignant solid tumor as inclusion criteria, 1 is phase 1 (1 open), 1 is phase 1/phase 2 (1 open), and 1 is phase 2 (1 open) .
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