Associated Genetic Biomarkers
BRAF G469L serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains BRAF G469L as an inclusion criterion, 1 is phase 1 (0 open).
Trials with BRAF G469L in the inclusion eligibility criteria most commonly target malignant solid tumor and non-small cell lung carcinoma .
Significance of BRAF G469L in Diseases
Malignant Solid Tumor +
Non-Small Cell Lung Carcinoma +
BRAF is mutated in 5.34% of non-small cell lung carcinoma patients .
BRAF G469L is an inclusion criterion in 1 clinical trial for non-small cell lung carcinoma, of which 0 are open and 1 is closed. Of the trial that contains BRAF G469L and non-small cell lung carcinoma as inclusion criteria, 1 is phase 1 (0 open) .
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Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.
4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.