Associated Genetic Biomarkers
BRAF I457_L717dup serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains BRAF I457_L717dup as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with BRAF I457_L717dup in the inclusion eligibility criteria most commonly target malignant solid tumor .
Binimetinib and encorafenib are the most frequent therapies in trials with BRAF I457_L717dup as an inclusion criteria .
Significance of BRAF I457_L717dup in Diseases
Malignant Solid Tumor +
BRAF is mutated in 39.82% of malignant solid tumor patients .
BRAF I457_L717dup is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains BRAF I457_L717dup and malignant solid tumor as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
Binimetinib and encorafenib are the most frequent therapies in trials for malignant solid tumor that contain BRAF I457_L717dup .
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