Associated Genetic Biomarkers
BRAF K601N is present in 0.03% of AACR GENIE cases, with lung adenocarcinoma having the greatest prevalence .
BRAF K601N serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains BRAF K601N as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with BRAF K601N in the inclusion eligibility criteria most commonly target malignant solid tumor .
Binimetinib and encorafenib are the most frequent therapies in trials with BRAF K601N as an inclusion criteria .
Significance of BRAF K601N in Diseases
Malignant Solid Tumor +
BRAF is altered in 5.41% of malignant solid tumor patients with BRAF K601N present in 0.03% of all malignant solid tumor patients .
BRAF K601N is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains BRAF K601N and malignant solid tumor as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
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