Overview

Gene Location [1]
19q13.12
Variant Type
Overexpression

Significance of CD22 Overexpression in Diseases

B-Cell Acute Lymphoblastic Leukemia +

Acute Lymphoblastic Leukemia +

Lymphoma +

Leukemia +

Hairy Cell Leukemia +

Non-Hodgkin Lymphoma +

Acute Biphenotypic Leukemia +

Acute Leukemia +

B-Cell Lymphoblastic Lymphoma +

B-Cell Non-Hodgkin Lymphoma +

B-Cell Prolymphocytic Leukemia +

Burkitt Leukemia +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20170629. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. Liu X, Wu C, Li C, and Boerwinkle E. dbNSFP v3.0: A one-stop database of functional predictions and annotations for human nonsynonymous and splice site SNVs. Human Mutation. 2015;37:235-241.

Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.

4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

5. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.