Associated Genetic Biomarkers
CDK1 Mutation is present in 0.49% of AACR GENIE cases, with lung adenocarcinoma, endometrial endometrioid adenocarcinoma, colon adenocarcinoma, anaplastic oligodendroglioma, and oral cavity squamous cell carcinoma having the greatest prevalence .
CDK1 Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains CDK1 Mutation as an inclusion criterion, 1 is phase 2 (1 open).
Trials with CDK1 Mutation in the inclusion eligibility criteria most commonly target malignant solid tumor .
Abemaciclib is the most frequent therapy in trials with CDK1 Mutation as an inclusion criteria .
Significance of CDK1 Mutation in Diseases
Malignant Solid Tumor +
CDK1 is altered in 0.81% of malignant solid tumor patients with CDK1 Mutation present in 0.55% of all malignant solid tumor patients .
CDK1 Mutation is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains CDK1 Mutation and malignant solid tumor as inclusion criteria, 1 is phase 2 (1 open) .
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