Associated Genetic Biomarkers
CEBPA Frameshift is present in 0.04% of AACR GENIE cases, with leukemia, colorectal adenocarcinoma, bladder carcinoma, breast carcinoma, and cancer of unknown primary having the greatest prevalence .
CEBPA Frameshift serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains CEBPA Frameshift as an inclusion criterion, 1 is phase 2 (1 open).
Trials with CEBPA Frameshift in the inclusion eligibility criteria most commonly target acute myeloid leukemia .
Midostaurin is the most frequent therapy in trials with CEBPA Frameshift as an inclusion criteria .
Significance of CEBPA Frameshift in Diseases
Acute Myeloid Leukemia +
CEBPA is mutated in 4.19% of acute myeloid leukemia patients with CEBPA Frameshift present in 1.2% of all acute myeloid leukemia patients .
CEBPA Frameshift is an inclusion criterion in 1 clinical trial for acute myeloid leukemia, of which 1 is open and 0 are closed. Of the trial that contains CEBPA Frameshift and acute myeloid leukemia as inclusion criteria, 1 is phase 2 (1 open) .
Midostaurin is the most frequent therapy in trials for acute myeloid leukemia that contain CEBPA Frameshift .
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