Associated Genetic Biomarkers
CRLF2 Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains CRLF2 Mutation as an inclusion criterion, 1 is phase 2 (1 open).
Significance of CRLF2 Mutation in Diseases
B-Cell Acute Lymphoblastic Leukemia +
CRLF2 Mutation is an inclusion criterion in 1 clinical trial for B-cell acute lymphoblastic leukemia, of which 1 is open and 0 are closed. Of the trial that contains CRLF2 Mutation and B-cell acute lymphoblastic leukemia as inclusion criteria, 1 is phase 2 (1 open) .
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3. Liu X, Wu C, Li C, and Boerwinkle E. dbNSFP v3.0: A one-stop database of functional predictions and annotations for human nonsynonymous and splice site SNVs. Human Mutation. 2015;37:235-241.
Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.
4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.