Associated Genetic Biomarkers
CRLF2 Mutation is present in 0.34% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, cutaneous melanoma, melanoma, and endometrial endometrioid adenocarcinoma having the greatest prevalence .
CRLF2 Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains CRLF2 Mutation as an inclusion criterion, 1 is phase 2 (1 open).
Significance of CRLF2 Mutation in Diseases
B-Cell Acute Lymphoblastic Leukemia +
CRLF2 Mutation is an inclusion criterion in 1 clinical trial for B-cell acute lymphoblastic leukemia, of which 1 is open and 0 are closed. Of the trial that contains CRLF2 Mutation and B-cell acute lymphoblastic leukemia as inclusion criteria, 1 is phase 2 (1 open) .
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4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.