Associated Genetic Biomarkers
CTNNA1 Mutation is present in 1.08% of AACR GENIE cases, with breast invasive ductal carcinoma, colon adenocarcinoma, lung adenocarcinoma, colorectal adenocarcinoma, and endometrial endometrioid adenocarcinoma having the greatest prevalence .
CTNNA1 Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains CTNNA1 Mutation as an inclusion criterion, 1 is phase 2/phase 3 (1 open).
Trials with CTNNA1 Mutation in the inclusion eligibility criteria most commonly target medulloblastoma .
Radiation therapy is the most frequent therapy in trials with CTNNA1 Mutation as an inclusion criteria .
Significance of CTNNA1 Mutation in Diseases
CTNNA1 Mutation is an inclusion criterion in 1 clinical trial for medulloblastoma, of which 1 is open and 0 are closed. Of the trial that contains CTNNA1 Mutation and medulloblastoma as inclusion criteria, 1 is phase 2/phase 3 (1 open) .
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