Associated Genetic Biomarkers
DNAJB1-PRKACA Fusion is present in 0.09% of AACR GENIE cases, with fibrolamellar carcinoma, hepatocellular carcinoma, pancreatic adenocarcinoma, and pancreatic intraductal papillary-mucinous neoplasm having the greatest prevalence .
DNAJB1-PRKACA Fusion serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains DNAJB1-PRKACA Fusion as an inclusion criterion, 1 is phase 1 (1 open).
Trials with DNAJB1-PRKACA Fusion in the inclusion eligibility criteria most commonly target fibrolamellar carcinoma .
Dnajb1-prkaca peptide vaccine, ipilimumab, and nivolumab are the most frequent therapies in trials with DNAJB1-PRKACA Fusion as an inclusion criteria .
Significance of DNAJB1-PRKACA Fusion in Diseases
Fibrolamellar Carcinoma +
DNAJB1-PRKACA Fusion is an inclusion criterion in 1 clinical trial for fibrolamellar carcinoma, of which 1 is open and 0 are closed. Of the trial that contains DNAJB1-PRKACA Fusion and fibrolamellar carcinoma as inclusion criteria, 1 is phase 1 (1 open) .
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