Associated Genetic Biomarkers
EGFR G719* serves as an inclusion eligibility criterion in 3 clinical trials, of which 3 are open and 0 are closed. Of the trials that contain EGFR G719* as an inclusion criterion, 1 is phase 1 (1 open) and 2 are phase 2 (2 open).
Trials with EGFR G719* in the inclusion eligibility criteria most commonly target non-small cell lung carcinoma and non-squamous non-small cell lung carcinoma .
Osimertinib, bintrafusp alfa, carboplatin, cisplatin, and navitoclax are the most frequent therapies in trials with EGFR G719* as an inclusion criteria .
Significance of EGFR G719* in Diseases
Non-Small Cell Lung Carcinoma +
EGFR is altered in 22.89% of non-small cell lung carcinoma patients .
EGFR G719* is an inclusion criterion in 2 clinical trials for non-small cell lung carcinoma, of which 2 are open and 0 are closed. Of the trials that contain EGFR G719* and non-small cell lung carcinoma as inclusion criteria, 1 is phase 1 (1 open) and 1 is phase 2 (1 open) .
Non-Squamous Non-Small Cell Lung Carcinoma +
EGFR is altered in 25.27% of non-squamous non-small cell lung carcinoma patients .
EGFR G719* is an inclusion criterion in 1 clinical trial for non-squamous non-small cell lung carcinoma, of which 1 is open and 0 are closed. Of the trial that contains EGFR G719* and non-squamous non-small cell lung carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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