Associated Genetic Biomarkers
ERBB2 D277Y is present in 0.02% of AACR GENIE cases, with lung adenocarcinoma, bladder urothelial carcinoma, adenocarcinoma of unknown primary, breast invasive ductal carcinoma, and colon adenocarcinoma having the greatest prevalence .
ERBB2 D277Y serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 D277Y as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with ERBB2 D277Y in the inclusion eligibility criteria most commonly target malignant solid tumor .
Bdtx-189 is the most frequent therapy in trials with ERBB2 D277Y as an inclusion criteria .
Significance of ERBB2 D277Y in Diseases
Malignant Solid Tumor +
ERBB2 is altered in 5.44% of malignant solid tumor patients with ERBB2 D277Y present in 0.02% of all malignant solid tumor patients .
ERBB2 D277Y is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 D277Y and malignant solid tumor as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
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