Associated Genetic Biomarkers
ERBB2 G776C is present in 0.09% of AACR GENIE cases, with infiltrating renal pelvis and ureter urothelial carcinoma and lung adenocarcinoma having the greatest prevalence .
ERBB2 G776C serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 G776C as an inclusion criterion, 1 is phase 2 (1 open).
Trials with ERBB2 G776C in the inclusion eligibility criteria most commonly target non-small cell lung carcinoma .
Docetaxel, pertuzumab, and trastuzumab are the most frequent therapies in trials with ERBB2 G776C as an inclusion criteria .
Significance of ERBB2 G776C in Diseases
Non-Small Cell Lung Carcinoma +
ERBB2 is altered in 3.97% of non-small cell lung carcinoma patients with ERBB2 G776C present in 0.01% of all non-small cell lung carcinoma patients .
ERBB2 G776C is an inclusion criterion in 1 clinical trial for non-small cell lung carcinoma, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 G776C and non-small cell lung carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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