Associated Genetic Biomarkers
ERBB2 L755_E757del is present in 0.04% of AACR GENIE cases, with invasive breast carcinoma having the greatest prevalence .
ERBB2 L755_E757del serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 L755_E757del as an inclusion criterion, 1 is phase 2 (1 open).
Trials with ERBB2 L755_E757del in the inclusion eligibility criteria most commonly target breast carcinoma .
Neratinib is the most frequent therapy in trials with ERBB2 L755_E757del as an inclusion criteria .
Significance of ERBB2 L755_E757del in Diseases
Breast Carcinoma +
ERBB2 is altered in 13.78% of breast carcinoma patients with ERBB2 L755_E757del present in 0.01% of all breast carcinoma patients .
ERBB2 L755_E757del is an inclusion criterion in 1 clinical trial for breast carcinoma, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 L755_E757del and breast carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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