Associated Genetic Biomarkers
ERBB2 L755A is present in 0.01% of AACR GENIE cases, with lung adenocarcinoma having the greatest prevalence .
ERBB2 L755A serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 L755A as an inclusion criterion, 1 is phase 2 (1 open).
Trials with ERBB2 L755A in the inclusion eligibility criteria most commonly target lung carcinoma .
Ado-trastuzumab emtansine is the most frequent therapy in trials with ERBB2 L755A as an inclusion criteria .
Significance of ERBB2 L755A in Diseases
Lung Carcinoma +
ERBB2 is altered in 3.91% of lung carcinoma patients with ERBB2 L755A present in 0.01% of all lung carcinoma patients .
ERBB2 L755A is an inclusion criterion in 1 clinical trial for lung carcinoma, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 L755A and lung carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
Malignant Solid Tumor +
ERBB2 is altered in 5.44% of malignant solid tumor patients with ERBB2 L755A present in 0.0% of all malignant solid tumor patients .
ERBB2 L755A is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 L755A and malignant solid tumor as inclusion criteria, 1 is phase 2 (1 open) .
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