Associated Genetic Biomarkers
ERBB2 R217C is present in 0.02% of AACR GENIE cases, with lung adenocarcinoma, conventional glioblastoma multiforme, myelodysplastic syndromes, pancreatic adenocarcinoma, and sarcoma, NOS having the greatest prevalence .
ERBB2 R217C serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 R217C as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with ERBB2 R217C in the inclusion eligibility criteria most commonly target malignant solid tumor .
Bdtx-189 is the most frequent therapy in trials with ERBB2 R217C as an inclusion criteria .
Significance of ERBB2 R217C in Diseases
Malignant Solid Tumor +
ERBB2 is altered in 5.44% of malignant solid tumor patients with ERBB2 R217C present in 0.01% of all malignant solid tumor patients .
ERBB2 R217C is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains ERBB2 R217C and malignant solid tumor as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
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