Associated Genetic Biomarkers
ERBB2 R868W is a predictive biomarker for use of ado-trastuzumab emtansine in patients.
Of the therapies with ERBB2 R868W as a predictive biomarker, 1 has NCCN guidelines in at least one clinical setting.
Non-small cell lung carcinoma has the most therapies targeted against ERBB2 R868W or its related pathways .
Ado-Trastuzumab Emtansine +
Non-Small Cell Lung Carcinoma -
|Biomarker Criteria:||Predicted Response: Primary Sensitivity|
|Clinical Setting(s): Metastatic (NCCN)|
|Note: Emerging Targeted Agent for patients with HER2 mutations, per NCCN.|
Significance of ERBB2 R868W in Diseases
Non-Small Cell Lung Carcinoma +
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