Associated Genetic Biomarkers
ERBB3 S846I is present in 0.03% of AACR GENIE cases, with breast invasive lobular carcinoma, colon adenocarcinoma, gastric adenocarcinoma, lung adenocarcinoma, and ampulla of vater carcinoma having the greatest prevalence .
ERBB3 S846I serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB3 S846I as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with ERBB3 S846I in the inclusion eligibility criteria most commonly target malignant solid tumor .
Bdtx-189 is the most frequent therapy in trials with ERBB3 S846I as an inclusion criteria .
Significance of ERBB3 S846I in Diseases
Malignant Solid Tumor +
ERBB3 is altered in 3.19% of malignant solid tumor patients with ERBB3 S846I present in 0.03% of all malignant solid tumor patients .
ERBB3 S846I is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains ERBB3 S846I and malignant solid tumor as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
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