Associated Genetic Biomarkers
ERBB3 V104M is present in 0.17% of AACR GENIE cases, with colon adenocarcinoma, endometrial endometrioid adenocarcinoma, rectal adenocarcinoma, gastric adenocarcinoma, and breast invasive ductal carcinoma having the greatest prevalence .
ERBB3 V104M serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ERBB3 V104M as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with ERBB3 V104M in the inclusion eligibility criteria most commonly target malignant solid tumor .
Bdtx-189 is the most frequent therapy in trials with ERBB3 V104M as an inclusion criteria .
Significance of ERBB3 V104M in Diseases
Malignant Solid Tumor +
ERBB3 is altered in 3.19% of malignant solid tumor patients with ERBB3 V104M present in 0.15% of all malignant solid tumor patients .
ERBB3 V104M is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains ERBB3 V104M and malignant solid tumor as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
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