ESR1 Codon 536 Missense
Associated Genetic Biomarkers
ESR1 Codon 536 Missense is present in 0.09% of AACR GENIE cases, with breast invasive ductal carcinoma, endometrial endometrioid adenocarcinoma, invasive breast carcinoma, unknown, and breast invasive lobular carcinoma having the greatest prevalence .
ESR1 Codon 536 Missense serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ESR1 Codon 536 Missense as an inclusion criterion, 1 is phase 2 (1 open).
Trials with ESR1 Codon 536 Missense in the inclusion eligibility criteria most commonly target breast carcinoma .
Fulvestrant and lasofoxifene are the most frequent therapies in trials with ESR1 Codon 536 Missense as an inclusion criteria .
Significance of ESR1 Codon 536 Missense in Diseases
Breast Carcinoma +
ESR1 is altered in 8.37% of breast carcinoma patients with ESR1 Codon 536 Missense present in 0.39% of all breast carcinoma patients .
ESR1 Codon 536 Missense is an inclusion criterion in 1 clinical trial for breast carcinoma, of which 1 is open and 0 are closed. Of the trial that contains ESR1 Codon 536 Missense and breast carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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