Associated Genetic Biomarkers
FANCA Nonsense is present in 0.14% of AACR GENIE cases, with lung adenocarcinoma, breast invasive ductal carcinoma, bladder urothelial carcinoma, colon adenocarcinoma, and colorectal adenocarcinoma having the greatest prevalence .
FANCA Nonsense serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains FANCA Nonsense as an inclusion criterion, 1 is phase 2 (1 open).
Trials with FANCA Nonsense in the inclusion eligibility criteria most commonly target prostate carcinoma .
Durvalumab and olaparib are the most frequent therapies in trials with FANCA Nonsense as an inclusion criteria .
Significance of FANCA Nonsense in Diseases
Prostate Carcinoma +
FANCA is altered in 2.72% of prostate carcinoma patients with FANCA Nonsense present in 0.03% of all prostate carcinoma patients .
FANCA Nonsense is an inclusion criterion in 1 clinical trial for prostate carcinoma, of which 1 is open and 0 are closed. Of the trial that contains FANCA Nonsense and prostate carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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