Associated Genetic Biomarkers
FGFR1 K656E is present in 0.04% of AACR GENIE cases, with conventional glioblastoma multiforme having the greatest prevalence .
FGFR1 K656E serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains FGFR1 K656E as an inclusion criterion, 1 is early phase 1 (1 open).
Trials with FGFR1 K656E in the inclusion eligibility criteria most commonly target malignant glioma .
Infigratinib is the most frequent therapy in trials with FGFR1 K656E as an inclusion criteria .
Significance of FGFR1 K656E in Diseases
Malignant Glioma +
FGFR1 is altered in 2.31% of malignant glioma patients with FGFR1 K656E present in 0.4% of all malignant glioma patients .
FGFR1 K656E is an inclusion criterion in 1 clinical trial for malignant glioma, of which 1 is open and 0 are closed. Of the trial that contains FGFR1 K656E and malignant glioma as inclusion criteria, 1 is early phase 1 (1 open) .
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