Associated Genetic Biomarkers
FGFR2 P253R is present in 0.04% of AACR GENIE cases, with endometrial endometrioid adenocarcinoma, breast invasive ductal carcinoma, breast invasive lobular carcinoma, diffuse intrinsic pontine glioma, and ductal carcinoma in situ having the greatest prevalence .
FGFR2 P253R serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains FGFR2 P253R as an inclusion criterion, 1 is no phase specified (0 open).
Trials with FGFR2 P253R in the inclusion eligibility criteria most commonly target endometrioid adenocarcinoma .
Ponatinib is the most frequent therapy in trials with FGFR2 P253R as an inclusion criteria .
Significance of FGFR2 P253R in Diseases
Endometrioid Adenocarcinoma +
FGFR2 is altered in 12.52% of endometrioid adenocarcinoma patients with FGFR2 P253R present in 0.52% of all endometrioid adenocarcinoma patients .
FGFR2 P253R is an inclusion criterion in 1 clinical trial for endometrioid adenocarcinoma, of which 0 are open and 1 is closed. Of the trial that contains FGFR2 P253R and endometrioid adenocarcinoma as inclusion criteria, 1 is no phase specified (0 open) .
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