Associated Genetic Biomarkers
FGFR3 G380R is present in 0.05% of AACR GENIE cases, with infiltrating renal pelvis and ureter urothelial carcinoma, bladder urothelial carcinoma, breast invasive ductal carcinoma, colorectal adenocarcinoma, and invasive breast carcinoma having the greatest prevalence .
FGFR3 G380R serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains FGFR3 G380R as an inclusion criterion, 1 is phase 1 (1 open).
Significance of FGFR3 G380R in Diseases
Urothelial Carcinoma +
FGFR3 is altered in 27.83% of urothelial carcinoma patients with FGFR3 G380R present in 0.47% of all urothelial carcinoma patients .
FGFR3 G380R is an inclusion criterion in 1 clinical trial for urothelial carcinoma, of which 1 is open and 0 are closed. Of the trial that contains FGFR3 G380R and urothelial carcinoma as inclusion criteria, 1 is phase 1 (1 open) .
Bladder Carcinoma +
FGFR3 is altered in 25.0% of bladder carcinoma patients with FGFR3 G380R present in 0.23% of all bladder carcinoma patients .
FGFR3 G380R is an inclusion criterion in 1 clinical trial for bladder carcinoma, of which 1 is open and 0 are closed. Of the trial that contains FGFR3 G380R and bladder carcinoma as inclusion criteria, 1 is phase 1 (1 open) .
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