HLA-DRA Expression serves as an inclusion eligibility criterion in 3 clinical trials, of which 2 are open and 1 is closed. Of the trials that contain HLA-DRA Expression as an inclusion criterion, 2 are phase 1 (2 open) and 1 is phase 2 (0 open).
Trials with HLA-DRA Expression in the inclusion eligibility criteria most commonly target myelodysplastic syndromes, acute myeloid leukemia, and melanoma .
Donor-derived wt1/prame/ny-eso-1/survivin-specific t-lymphocytes, decitabine, nivolumab, pembrolizumab, and relatlimab are the most frequent therapies in trials with HLA-DRA Expression as an inclusion criteria .
Significance of HLA-DRA Expression in Diseases
Acute Myeloid Leukemia +
HLA-DRA Expression is an inclusion criterion in 2 clinical trials for acute myeloid leukemia, of which 2 are open and 0 are closed. Of the trials that contain HLA-DRA Expression and acute myeloid leukemia as inclusion criteria, 2 are phase 1 (2 open) .
Myelodysplastic Syndromes +
HLA-DRA Expression is an inclusion criterion in 2 clinical trials for myelodysplastic syndromes, of which 2 are open and 0 are closed. Of the trials that contain HLA-DRA Expression and myelodysplastic syndromes as inclusion criteria, 2 are phase 1 (2 open) .
HLA-DRA Expression is an inclusion criterion in 1 clinical trial for melanoma, of which 0 are open and 1 is closed. Of the trial that contains HLA-DRA Expression and melanoma as inclusion criteria, 1 is phase 2 (0 open) .
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