Associated Genetic Biomarkers
INPP4A Loss is present in 0.02% of AACR GENIE cases, with bladder urothelial carcinoma, dedifferentiated liposarcoma, high grade ovarian serous adenocarcinoma, lung adenocarcinoma, and lung neuroendocrine neoplasm having the greatest prevalence .
INPP4A Loss serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains INPP4A Loss as an inclusion criterion, 1 is phase 1 (1 open).
Trials with INPP4A Loss in the inclusion eligibility criteria most commonly target malignant solid tumor .
Paxalisib and radiation therapy are the most frequent therapies in trials with INPP4A Loss as an inclusion criteria .
Significance of INPP4A Loss in Diseases
Malignant Solid Tumor +
INPP4A is altered in 1.38% of malignant solid tumor patients with INPP4A Loss present in 0.01% of all malignant solid tumor patients .
INPP4A Loss is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains INPP4A Loss and malignant solid tumor as inclusion criteria, 1 is phase 1 (1 open) .
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