Associated Genetic Biomarkers
INPP4B Loss is present in 0.07% of AACR GENIE cases, with small cell lung carcinoma, anaplastic astrocytoma, colon adenocarcinoma, hepatocellular carcinoma, and high grade ovarian serous adenocarcinoma having the greatest prevalence .
INPP4B Loss serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains INPP4B Loss as an inclusion criterion, 1 is phase 1 (1 open).
Trials with INPP4B Loss in the inclusion eligibility criteria most commonly target malignant solid tumor .
Paxalisib and radiation therapy are the most frequent therapies in trials with INPP4B Loss as an inclusion criteria .
Significance of INPP4B Loss in Diseases
Malignant Solid Tumor +
INPP4B is altered in 1.41% of malignant solid tumor patients with INPP4B Loss present in 0.04% of all malignant solid tumor patients .
INPP4B Loss is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains INPP4B Loss and malignant solid tumor as inclusion criteria, 1 is phase 1 (1 open) .
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