Associated Genetic Biomarkers
KDR Frameshift is present in 0.09% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, prostate adenocarcinoma, colorectal adenocarcinoma, and astrocytoma having the greatest prevalence .
KDR Frameshift serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains KDR Frameshift as an inclusion criterion, 1 is phase 2 (0 open).
Significance of KDR Frameshift in Diseases
Non-Small Cell Lung Carcinoma +
KDR is altered in 3.82% of non-small cell lung carcinoma patients with KDR Frameshift present in 0.16% of all non-small cell lung carcinoma patients .
KDR Frameshift is an inclusion criterion in 1 clinical trial for non-small cell lung carcinoma, of which 0 are open and 1 is closed. Of the trial that contains KDR Frameshift and non-small cell lung carcinoma as inclusion criteria, 1 is phase 2 (0 open) .
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4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.