Associated Genetic Biomarkers
KIT V560D is present in 0.02% of AACR GENIE cases, with gastrointestinal stromal tumor, anorectal melanoma, cutaneous melanoma, poorly differentiated non-small cell lung cancer, and therapy-related myelodysplastic syndrome having the greatest prevalence .
KIT V560D is a predictive biomarker for use of sorafenib and sunitinib in patients.
Melanoma has the most therapies targeted against KIT V560D or its related pathways .
Significance of KIT V560D in Diseases
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