Associated Genetic Biomarkers
KIT V654A is present in 0.04% of AACR GENIE cases, with connective and soft tissue neoplasm and melanoma having the greatest prevalence .
KIT V654A is a predictive biomarker for use of imatinib and sunitinib in patients.
Melanoma has the most therapies targeted against KIT V654A or its related pathways .
Significance of KIT V654A in Diseases
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