Associated Genetic Biomarkers
MAPK1 Fusion is present in 0.02% of AACR GENIE cases, with invasive breast carcinoma, anorectal melanoma, endometrial serous adenocarcinoma, esophageal adenocarcinoma, and ovarian yolk sac tumor having the greatest prevalence .
MAPK1 Fusion serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains MAPK1 Fusion as an inclusion criterion, 1 is phase 2 (1 open).
Trials with MAPK1 Fusion in the inclusion eligibility criteria most commonly target malignant solid tumor .
Abemaciclib and temuterkib are the most frequent therapies in trials with MAPK1 Fusion as an inclusion criteria .
Significance of MAPK1 Fusion in Diseases
Malignant Solid Tumor +
MAPK1 Fusion is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains MAPK1 Fusion and malignant solid tumor as inclusion criteria, 1 is phase 2 (1 open) .
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