Associated Genetic Biomarkers
MECOM Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains MECOM Mutation as an inclusion criterion, 1 is phase 2 (1 open).
Trials with MECOM Mutation in the inclusion eligibility criteria most commonly target acute myeloid leukemia and myelodysplastic syndromes .
Donor lymphocytes and guadecitabine are the most frequent therapies in trials with MECOM Mutation as an inclusion criteria .
Significance of MECOM Mutation in Diseases
Acute Myeloid Leukemia +
MECOM is altered in 1.36% of acute myeloid leukemia patients with MECOM Mutation present in 1.02% of all acute myeloid leukemia patients .
MECOM Mutation is an inclusion criterion in 1 clinical trial for acute myeloid leukemia, of which 1 is open and 0 are closed. Of the trial that contains MECOM Mutation and acute myeloid leukemia as inclusion criteria, 1 is phase 2 (1 open) .
Myelodysplastic Syndromes +
MECOM is altered in 0.82% of myelodysplastic syndromes patients with MECOM Mutation present in 0.85% of all myelodysplastic syndromes patients .
MECOM Mutation is an inclusion criterion in 1 clinical trial for myelodysplastic syndromes, of which 1 is open and 0 are closed. Of the trial that contains MECOM Mutation and myelodysplastic syndromes as inclusion criteria, 1 is phase 2 (1 open) .
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