Associated Genetic Biomarkers
MERTK Mutation is present in 4.15% of AACR GENIE cases, with endometrial carcinoma, rectal adenocarcinoma, adenocarcinoma of unknown primary, bladder urothelial carcinoma, and cancer of unknown primary, NOS having the greatest prevalence .
MERTK Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains MERTK Mutation as an inclusion criterion, 1 is phase 2 (1 open).
Trials with MERTK Mutation in the inclusion eligibility criteria most commonly target malignant solid tumor .
Cabozantinib is the most frequent therapy in trials with MERTK Mutation as an inclusion criteria .
Significance of MERTK Mutation in Diseases
Malignant Solid Tumor +
MERTK is altered in 3.76% of malignant solid tumor patients with MERTK Mutation present in 3.76% of all malignant solid tumor patients .
MERTK Mutation is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains MERTK Mutation and malignant solid tumor as inclusion criteria, 1 is phase 2 (1 open) .
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