Associated Genetic Biomarkers
NBN Deletion is present in 0.01% of AACR GENIE cases.
NBN Deletion serves as an inclusion eligibility criterion in 2 clinical trials, of which 2 are open and 0 are closed. Of the trials that contain NBN Deletion as an inclusion criterion, 2 are phase 2 (2 open).
Trials with NBN Deletion in the inclusion eligibility criteria most commonly target breast carcinoma and pancreatic adenocarcinoma .
Olaparib is the most frequent therapy in trials with NBN Deletion as an inclusion criteria .
Significance of NBN Deletion in Diseases
Breast Carcinoma +
Pancreatic Adenocarcinoma +
NBN is mutated in 0.92% of pancreatic adenocarcinoma patients .
NBN Deletion is an inclusion criterion in 1 clinical trial for pancreatic adenocarcinoma, of which 1 is open and 0 are closed. Of the trial that contains NBN Deletion and pancreatic adenocarcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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