Associated Genetic Biomarkers
NPM1-RARA Fusion is present in 0.08% of AACR GENIE cases, with invasive breast carcinoma, lung adenocarcinoma, breast invasive ductal carcinoma, esophageal adenocarcinoma, and acute myeloid leukemia having the greatest prevalence .
NPM1-RARA Fusion serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains NPM1-RARA Fusion as an inclusion criterion, 1 is phase 3 (1 open).
Trials with NPM1-RARA Fusion in the inclusion eligibility criteria most commonly target acute myeloid leukemia .
Beta all trans retinoic acid and idarubicin are the most frequent therapies in trials with NPM1-RARA Fusion as an inclusion criteria .
Significance of NPM1-RARA Fusion in Diseases
Acute Myeloid Leukemia +
NPM1-RARA Fusion is an inclusion criterion in 1 clinical trial for acute myeloid leukemia, of which 1 is open and 0 are closed. Of the trial that contains NPM1-RARA Fusion and acute myeloid leukemia as inclusion criteria, 1 is phase 3 (1 open) .
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