Associated Genetic Biomarkers
PIK3R3 Mutation is present in 0.48% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, endometrial endometrioid adenocarcinoma, breast invasive ductal carcinoma, and cutaneous melanoma having the greatest prevalence .
PIK3R3 Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains PIK3R3 Mutation as an inclusion criterion, 1 is phase 1 (1 open).
Trials with PIK3R3 Mutation in the inclusion eligibility criteria most commonly target malignant solid tumor .
Paxalisib and radiation therapy are the most frequent therapies in trials with PIK3R3 Mutation as an inclusion criteria .
Significance of PIK3R3 Mutation in Diseases
Malignant Solid Tumor +
PIK3R3 is altered in 0.69% of malignant solid tumor patients with PIK3R3 Mutation present in 0.49% of all malignant solid tumor patients .
PIK3R3 Mutation is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains PIK3R3 Mutation and malignant solid tumor as inclusion criteria, 1 is phase 1 (1 open) .
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