Associated Genetic Biomarkers
RAD51C Nonsense is present in 0.07% of AACR GENIE cases, with bladder urothelial carcinoma, endometrial endometrioid adenocarcinoma, high grade ovarian serous adenocarcinoma, lung adenocarcinoma, and adenocarcinoma of unknown primary having the greatest prevalence .
RAD51C Nonsense serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains RAD51C Nonsense as an inclusion criterion, 1 is phase 2 (1 open).
Trials with RAD51C Nonsense in the inclusion eligibility criteria most commonly target prostate carcinoma .
Durvalumab and olaparib are the most frequent therapies in trials with RAD51C Nonsense as an inclusion criteria .
Significance of RAD51C Nonsense in Diseases
Prostate Carcinoma +
RAD51C is altered in 0.54% of prostate carcinoma patients .
RAD51C Nonsense is an inclusion criterion in 1 clinical trial for prostate carcinoma, of which 1 is open and 0 are closed. Of the trial that contains RAD51C Nonsense and prostate carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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