SF3B1 Codon 622 Missense
Associated Genetic Biomarkers
SF3B1 Codon 622 Missense is present in 0.05% of AACR GENIE cases, with chronic lymphocytic leukemia/small lymphocytic lymphoma, myelodysplastic syndromes, prostate adenocarcinoma, myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia, and refractory cytopenia with multilineage dysplasia and ring sideroblasts having the greatest prevalence .
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4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.