Associated Genetic Biomarkers
STAT4 Mutation is present in 1.59% of AACR GENIE cases, with cutaneous melanoma, colon adenocarcinoma, melanoma, conventional glioblastoma multiforme, and lung adenocarcinoma having the greatest prevalence .
STAT4 Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains STAT4 Mutation as an inclusion criterion, 1 is phase 2 (0 open).
Trials with STAT4 Mutation in the inclusion eligibility criteria most commonly target malignant solid tumor .
Irinotecan and sorafenib are the most frequent therapies in trials with STAT4 Mutation as an inclusion criteria .
Significance of STAT4 Mutation in Diseases
Malignant Solid Tumor +
STAT4 is altered in 1.94% of malignant solid tumor patients with STAT4 Mutation present in 1.8% of all malignant solid tumor patients .
STAT4 Mutation is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 0 are open and 1 is closed. Of the trial that contains STAT4 Mutation and malignant solid tumor as inclusion criteria, 1 is phase 2 (0 open) .
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