Associated Genetic Biomarkers
STAT5A Mutation is present in 0.55% of AACR GENIE cases, with colon adenocarcinoma, lung adenocarcinoma, endometrial endometrioid adenocarcinoma, breast invasive ductal carcinoma, and cutaneous melanoma having the greatest prevalence .
STAT5A Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains STAT5A Mutation as an inclusion criterion, 1 is phase 2 (0 open).
Trials with STAT5A Mutation in the inclusion eligibility criteria most commonly target malignant solid tumor .
Irinotecan and sorafenib are the most frequent therapies in trials with STAT5A Mutation as an inclusion criteria .
Significance of STAT5A Mutation in Diseases
Malignant Solid Tumor +
STAT5A is altered in 0.98% of malignant solid tumor patients with STAT5A Mutation present in 0.63% of all malignant solid tumor patients .
STAT5A Mutation is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 0 are open and 1 is closed. Of the trial that contains STAT5A Mutation and malignant solid tumor as inclusion criteria, 1 is phase 2 (0 open) .
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