Associated Genetic Biomarkers
STAT5B Mutation is present in 0.65% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, cutaneous melanoma, endometrial endometrioid adenocarcinoma, and bladder urothelial carcinoma having the greatest prevalence .
STAT5B Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains STAT5B Mutation as an inclusion criterion, 1 is phase 2 (0 open).
Trials with STAT5B Mutation in the inclusion eligibility criteria most commonly target malignant solid tumor .
Irinotecan and sorafenib are the most frequent therapies in trials with STAT5B Mutation as an inclusion criteria .
Significance of STAT5B Mutation in Diseases
Malignant Solid Tumor +
STAT5B is altered in 0.87% of malignant solid tumor patients with STAT5B Mutation present in 0.67% of all malignant solid tumor patients .
STAT5B Mutation is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 0 are open and 1 is closed. Of the trial that contains STAT5B Mutation and malignant solid tumor as inclusion criteria, 1 is phase 2 (0 open) .
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