Associated Genetic Biomarkers
TERT Mutation is present in 1.83% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, cutaneous melanoma, endometrial endometrioid adenocarcinoma, and conventional glioblastoma multiforme having the greatest prevalence .
TERT Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains TERT Mutation as an inclusion criterion, 1 is phase 2 (1 open).
Trials with TERT Mutation in the inclusion eligibility criteria most commonly target glioblastoma and glioblastoma, IDH-wildtype .
Dendritic cell vaccine and placebo are the most frequent therapies in trials with TERT Mutation as an inclusion criteria .
Significance of TERT Mutation in Diseases
TERT is altered in 3.77% of glioblastoma patients with TERT Mutation present in 2.92% of all glioblastoma patients .
TERT Mutation is an inclusion criterion in 1 clinical trial for glioblastoma, of which 1 is open and 0 are closed. Of the trial that contains TERT Mutation and glioblastoma as inclusion criteria, 1 is phase 2 (1 open) .
Glioblastoma, IDH-Wildtype +
TERT Mutation is an inclusion criterion in 1 clinical trial for glioblastoma, IDH-wildtype, of which 1 is open and 0 are closed. Of the trial that contains TERT Mutation and glioblastoma, IDH-wildtype as inclusion criteria, 1 is phase 2 (1 open) .
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