Associated Genetic Biomarkers
TOP2A Amplification is present in 0.21% of AACR GENIE cases.
TOP2A Amplification serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains TOP2A Amplification as an inclusion criterion, 1 is phase 2 (1 open).
Significance of TOP2A Amplification in Diseases
Breast Carcinoma +
TOP2A Amplification is an inclusion criterion in 1 clinical trial for breast carcinoma, of which 1 is open and 0 are closed. Of the trial that contains TOP2A Amplification and breast carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.