Inclusion Criteria:

          -  Histologically or cytologically confirmed diagnosis of nonsquamous NSCLC that is Stage
             IIIB, Stage IV, or recurrent (including Stage II).

          -  Documented evidence of an activating mutation in EGFR in tumor samples (exon 19
             deletions or point mutation L858R in exon 21 or point mutations at codon 719).

          -  A mGPS of 1 or 2 as defined below:

               -  Criteria: C-reactive protein >10 mg/L AND albumin ≥35 g/L Score-1

               -  Criteria: C-reactive protein >10 mg L AND albumin <35 g/L Score-2

          -  Radiographically measurable or evaluable disease.

          -  Life expectancy of at least 12 weeks.

          -  Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2.

          -  Adequate renal, hepatic, and bone marrow function demonstrated by protocol-specified
             laboratory parameters at the screening visit.

        Exclusion Criteria:

          -  Known presence of the T790M mutation in EGFR in tumor samples

          -  Candidates for curative radiation therapy or surgery.

          -  Previous systemic chemotherapy for advanced disease, including EGFR inhibitor therapy,
             except subjects who received 1 cycle of chemotherapy while waiting to receive EGFR
             results, who may enroll provided that 21 days have elapsed from end of chemotherapy to
             the day to the baseline radiographic measurement prior to Cycle 1 Day 1.

          -  Distinct or suspected, or history of, pulmonary fibrosis or ILD.

          -  Current or previous other malignancy within 2 years of study entry, except cured basal
             or squamous cell skin cancer, superficial bladder cancer, prostate intraepithelial
             neoplasm, carcinoma in situ of the cervix, or other noninvasive indolent or Stage I
             malignancy without sponsor approval.