Inclusion Criteria

          -  Have histological or cytological evidence of a diagnosis of solid tumor that is
             advanced and/or metastatic and must be, in the judgment of the investigator, an
             appropriate candidate for experimental therapy after available standard therapies have
             failed or for whom standard therapy would not be appropriate.

          -  Have the presence of measurable or non-measurable disease as defined by Response
             Evaluation Criteria in Solid Tumors (RECIST) version 1.1.

          -  Have adequate organ and coagulation function.

          -  Have discontinued all previous cancer therapies, and any agents that have not received
             regulatory approval for any indication, for at least 21 days or 5 half-lives prior to
             study treatment, whichever is shorter, and recovered from the acute effects of
             therapy. Participants must have discontinued mitomycin-C or nitrosourea therapy for at
             least 42 days.

          -  Are able to swallow capsules.

          -  Males must agree to use medically approved barrier contraceptive precautions during
             the study and for 3 months following the last dose of study drug.

          -  Females with childbearing potential: Must agree to use medically approved
             contraceptive precautions during the study and for 3 months following the last dose of
             study drug, must have had a negative serum or urine pregnancy test ≤7 days before the
             first dose of study drug.

          -  A breastfeeding woman must not be breastfeeding. If a female who stops breastfeeding
             enters the study, breastfeeding must cease from the day of the first study drug
             administration until at least 3 months after the last administration.

        Exclusion Criteria

          -  Have serious pre-existing medical conditions.

          -  Have symptomatic central nervous system malignancy or metastasis.

          -  Have known acute or chronic leukemia or current hematologic malignancies that, in the
             judgment of the investigator and sponsor, may affect the interpretation of results.

          -  Have a known active fungal, bacterial, and/or known viral infection.

          -  Intolerance to any previous treatment with any phosphatidylinositol 3-kinase
             (PI3K)/AKT/mammalian target of rapamycin (mTOR) inhibitor. Treatment with any
             PI3K/AKT/mTOR inhibitor must have discontinued for at least 21 days or 5 half-lives
             prior to first study drug administration, whichever is shorter, and participants must
             have recovered from the acute effects of therapy.

          -  Have a second primary malignancy that, in the judgment of the investigator, and
             sponsor may affect the interpretation of results.

          -  Participants with active alcohol abuse, as determined by the investigator.

          -  Have a history of heart failure according to New York Heart Association Class ≥3.

          -  Have corrected QT (QTc) interval of >470 milliseconds (msec) on screening
             electrocardiogram (ECG).

          -  Have insulin-dependent diabetes mellitus or a history of gestational diabetes
             mellitus.

          -  Have any evidence of clinically active interstitial lung disease (ILD).