Inclusion Criteria:

        Male and female subjects with MUC1+ malignancies in patients with no available curative
        treatment options who have limited prognosis (several months to < 2 year survival) with
        currently available therapies will be enrolled:

          -  Eligible diseases: MUC1+ hepatocellular carcinoma, non-small cell lung cancer,
             pancreatic carcinoma and triple-negative basal-like breast carcinoma.

               1. Hepatocellular carcinoma (HCC)

                  Clinical diagnosis of HCC was confirmed by histopathological examination of
                  surgical samples in all patients;

               2. Non-small cell lung cancer

                  Refractory or recurrent histologically or cytologically confirmed; unresectable;
                  non-squamous NSCLC must have been tested for epidermal growth factor receptor
                  (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocation and if
                  positive should have received appropriate tyrosine kinase inhibitor therapy prior
                  to enrollment;

               3. Pancreatic carcinoma

                  Patients with histologic verification of carcinoma of the pancreas (T1-3, N0-1)
                  who have undergone surgical resection within the past 4 - 12 weeks. Patients with
                  R1 resections are excluded;

               4. Triple-negative basal-like breast carcinoma

                  Patients with basal-like breast carcinoma must have confirmed triple negative
                  (estrogen receptor negative [ER-]/ progesterone receptor (PR) negative [PR-]/
                  human epidermal growth factor receptor-2 (HER2) negative [HER2-]) .

          -  MUC1 is expressed in malignancy tissues by immuno-histochemical (IHC).

          -  Eastern cooperative oncology group (ECOG) performance status of 0-1 or karnofsky
             performance status (KPS) score is higher than 60.

          -  Patients 18 years of age or older, and must have a life expectancy > 12 weeks.

          -  Adequate venous access for apheresis or venous sampling, and no other
             contraindications for leukapheresis.

          -  Females of child-bearing potential must have a negative pregnancy test and all
             subjects must agree to use an effective method of contraception for up to two weeks
             after the last infusion of CAR T cells.

          -  Adequate bone marrow, liver and renal function as assessed by the following laboratory
             requirements: White blood cell count (WBC) ≥ 2500c/ml, Platelets ≥ 50×10^9/L, Hb ≥
             9.0g/dL, lymphocyte (LY) ≥ 0.7×10^9/L, LY% ≥ 15%, Alb ≥ 2.8g/dL, serum lipase and
             amylase < 1.5×upper limit of normal, serum creatinine ≤ 2.5mg/dL, aspartate
             aminotransferase (AST) and alanine aminotransferase (ALT) ≤ 5×upper limit of normal,
             serum total bilirubin ≤ 2.0mg/dL. These tests must be conducted within 7 days prior to
             registration.

          -  Ability to give informed consent.

        Exclusion Criteria:

          -  The transduction efficiency of the T cells is less than 10% or the amplification of
             the T cells via artificial antigen presenting cell (aAPC) stimulation is less than 5
             times.

          -  Patients with symptomatic central nervous system (CNS) involvement.

          -  Pregnant or nursing women may not participate.

          -  Known HIV, hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.

          -  Serious illness or medical condition which would not permit the patient to be managed
             according to the protocol, including active uncontrolled infection, major
             cardiovascular, coagulation disorders, respiratory or immune system, myocardial
             infarction, cardiac arrhythmias, obstructive/restrictive pulmonary disease, or
             psychiatric or emotional disorders.

          -  History of severe immediate hypersensitivity to any of the agents including
             cyclophosphamide, fludarabine, or aldesleukin.

          -  Concurrent use of systemic steroids. Recent or current use of inhaled steroids is not
             exclusionary.

          -  Previously treatment with any gene therapy products.

          -  The existence of unstable or active ulcers or gastrointestinal bleeding.

          -  Patients with portal vein vascular invasion or extrahepatic, are excluded from this
             study.

          -  Patients with a history of organ transplantation or are waiting for organ
             transplantation.

          -  Patients need anticoagulant therapy (such as warfarin or heparin).

          -  Patients need long-term antiplatelet therapy (aspirin at a dose > 300mg/d; clopidogrel
             at a dose > 75mg/d).

          -  Patients treated by radiotherapy within 4 weeks prior the first apheresis.

          -  Patients using fludarabine or cladribine chemotherapy within two years.