Inclusion Criteria:

          -  Male or female patients ≥ 18 years of age

          -  Patients with a histologically confirmed solid tumor:

               -  Tumor must harbor an IDH1-R132X mutation

               -  Disease must be evaluable as per RECIST 1.1 or RANO (for gliomas). At least one
                  measurable target lesion is required in expansion cohort patients

               -  Patients with advanced cancer who are refractory to, have demonstrated
                  intolerance to, or have refused access to, available standard therapies

               -  Glioma patients must have completed chemoradiotherapy at least 12 weeks prior to
                  screening and their baseline scan

          -  Patient must be able to provide a formalin-fixed and paraffin-embedded (FFPE) tumor
             tissue specimen prior to treatment. The specimen may have been taken at any time
             during the course of the disease and may be from the primary tumor or from a
             metastasis

          -  Patient must be able to take oral medication and comply with protocol procedures and
             scheduled visits

          -  Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1

          -  Negative serum or urine pregnancy test must be obtained within 7 days prior to the
             first dose of study drug in women of childbearing potential. Negative results must be
             available prior to study drug administration. Pregnancy tests will be repeated
             regularly during treatment

          -  Sexually active women and men of reproductive potential must agree to use highly
             effective contraception. This applies for the period between signing of the informed
             consent and 3 months after the last administration of study drug. These procedures
             should be documented in source documents. The investigator or a designated associate
             is requested to advise the patient on how to achieve highly effective birth control.
             Highly effective contraception includes:

               -  Established use of oral, injected or implanted hormonal methods of contraception

               -  Placement of certain intrauterine devices (IUD) or intrauterine systems (IUS)

               -  Hysterectomy, or vasectomy of the partner (provided that partner is the sole
                  sexual partner of the woman of childbearing potential trial participant and that
                  the vasectomized partner has received medical assessment of the surgical success)
                  In addition, the use of condoms for patients or their partners is required

          -  Ability to understand and the willingness to sign a written informed consent. A signed
             informed consent, including consent for biomarker analyses, must be obtained prior to
             any study-specific procedures

          -  Adequate blood clotting as defined by international normalized ratio (INR) and
             activated partial thromboplastin time (aPTT) ≤ 1.5 times ULN (patients on
             anticoagulation with an agent such as warfarin or heparin or rivoraxaban will be
             allowed to participate provided that no prior evidence of underlying abnormality in
             these parameters exists). For patients on warfarin, close monitoring of at least
             weekly evaluations will be performed until INR is stable based on a measurement at
             pre-dose, as defined by the local standard of care

          -  Adequate bone marrow, liver, and renal functions as assessed by the following
             laboratory requirements to be conducted within 7 days prior to the first dose of study
             drug:

               -  Hemoglobin ≥ 9.0 g/dL;

               -  Absolute neutrophil count (ANC) ≥ 1.5x10^9/L;

               -  Platelet count ≥ 100x10^9/L.

               -  Total bilirubin ≤ 1.5 times the upper limit of normal (ULN). For intrahepatic
                  cholangiocarcinoma (IHCC) patients only, total bilirubin ≤ 2.5 times ULN is
                  acceptable

               -  Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times
                  ULN (≤ 5 times ULN for patients with impaired liver function due primary tumor or
                  metastatic disease)

               -  Estimated glomerular filtration rate (eGFR) ≥ 40 mL/min per 1.73 m^2 according to
                  the Modification of Diet in Renal Disease Study Group (MDRD) formula

          -  Minimum life expectancy of 3 months per the judgment of the investigator

        Exclusion Criteria:

          -  Known hypersensitivity to the study drug or excipients of the preparation or any agent
             given in association with this study

          -  History of cardiac disease, including congestive heart failure of New York Heart
             Association (NYHA) class >II, unstable angina (anginal symptoms at rest) or new-onset
             angina (within 6 months prior to study entry), myocardial infarction within 6 months
             prior to study entry, or cardiac arrhythmias requiring anti-arrhythmic therapy except
             for beta-blockers and digoxin; evidence for uncontrolled coronary artery disease (e.g.
             angina pectoris, myocardial infarction within 6 months prior to study entry, major
             regional wall motion abnormalities upon baseline echocardiography or multiple-gated
             acquisition [MUGA] scan). Patients with a pacemaker are also excluded

          -  Left ventricular ejection fraction (LVEF) < 40% as measured by echocardiography or
             MUGA scan performed at Screening

          -  Uncontrolled hypertension defined as systolic blood pressure ≥ 160 mmHg or diastolic
             blood pressure ≥ 100 mmHg, despite medical management

          -  Patients who have an active clinically significant infection of the National Cancer
             Institute Common Terminology Criteria for Adverse Events (CTCAE) grade ≥ 2

          -  Previous or coexisting cancer(s) distinct in primary site or histology from the cancer
             evaluated in this study EXCEPT:

               -  Appropriately treated cervical cancer in-situ, non-melanoma skin cancers, or
                  superficial bladder tumors (Ta and Tis)

               -  Any cancer that was curatively treated at least 3 years before entry into this
                  study

          -  Unresolved specific chronic toxicity of previous treatment of grade > 1 except for
             alopecia or hemoglobin ≤9.0 g/dL (or ≤5.6 mmol/L)

          -  Major surgery, significant trauma, wide-field radiotherapy, or therapy with monoclonal
             antibodies within 4 weeks before the first dose of study drug

          -  Treatment with investigational or approved anti-cancer drugs within 4 weeks before the
             start of BAY1436032 treatment and during the study (glioma patients must have
             completed chemoradiotherapy at least 12 weeks prior to screening and their baseline
             scan; see inclusion criteria #2)

          -  Pregnant women. Women of reproductive potential must have a negative serum or urine
             pregnancy test performed within 7 day

          -  Prior treatment with any therapy targeting mutant IDH1 (including BAY1436032)